Molecular Interaction Exchange

The International Molecular Exchange Consortium IMEx is the latest effort of data-providers to integrate Protein-Interaction Data –

IMEx provides

  • A non-redundant set of protein-protein interaction data from a broad taxonomic range of organisms
  • the data in standards compliant download formats (MITAB or PSI-MI XML 2.5)
  • Expertly curated from direct submissions or peer-reviewed journals to a consistent high standard.
[ … aiming to … ]
  • Develop and work to a single set of curation rules when capturing data from both directly deposited interaction data or from publications in peer-reviewed journals
  • Make these interaction available in a single search interface on a common website
  • Make all IMEx records freely accessible under the Creative Commons Attribution License

If you’ve been looking for that one-stop shop for getting a representative dataset of Protein-Protein Interactions, this just looks like it. There is an overview available on youtube (see below)

… and a training course on “Networks and Pathways Bioinformatics for Biologists” will take place at EMBL-EBI in May.

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  1. #1 by cistronic on 2012/03/08 - 11:31

    Along the same lines, see
    http://www.integrativebiology.org/

    described in “IMID: integrated molecular interaction database” by Sentil Balaji et al.
    http://bioinformatics.oxfordjournals.org/content/28/5/747

  2. #2 by cistronic on 2012/03/16 - 11:15

    Also, the Protein Interactions and Networks Advanced Course (19-25 August 2012, Wellcome Trust Genome Campus, Hinxton, Cambridge – Deadline for applications: 4 May 2012) might be of interest here:
    http://www.wellcome.ac.uk/Education-resources/Courses-and-conferences/Advanced-Courses-and-Scientific-Conferences/Advanced-Courses/WTVM049891.htm

  3. #3 by cistronic on 2012/03/30 - 14:23

    Further Info: see the EMBL-EBI press release “Major networking opportunity: IMEx Consortium brings interactomes to light”
    http://www.ebi.ac.uk/Information/News/press-releases/press-release-26032012-Imex.html

    and the nature methods publication by S. Orchard, et al. (2012). “Protein interaction data curation: the International Molecular Exchange (IMEx) consortium.” Nature Methods 9(4), 345-350. Published online 27 March 2012; doi: 10.1038/nmeth.1931
    http://www.nature.com/nmeth/journal/v9/n4/full/nmeth.1931.html

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